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If appropriate, a statistical reviewer is involved. The drug to treat schistosomiasis is praziquantel and there is a huge need for improved access to this drug, which will only come about with improved international recognition of the importance of this disease if untreated, by causing malnutrition in children and serious consequences in later life. If you require the return of any material submitted, please inform the editorial office or production editor as soon as possible if you have not yet done so. As of early , 14 vaccine candidates have entered clinical trials and 11 are currently undergoing clinical testing. The Mesoamerica region has witnessed a downward trend of transmission, with current levels reaching historically low levels in many areas and the disease having virtually disappeared in some places. Despite many advances, further studies are still needed to better understand the role of viruses in the cause and pathogenesis of CAP and this will guide antiviral drug and vaccine developments. Articles are therefore available as soon as they are ready, rather thatn having to wait for the next scheduled print issue. The emergence of arboviruses, the increase in international travel and the spread of mosquito vectors contribute to put areas at risk of arboviral epidemics. The village is surrounded by irrigated crops, mainly maize, alfalfa and vegetables, but also rice crops 2 km away.

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